RIN2 antibody

Catalog No. ABIN6568165

This anti-RIN2 antibody is a Rabbit Polyclonal antibody detecting RIN2 in WB. Suitable for Human and Mouse.

Quick Overview for RIN2 antibody (ABIN6568165)

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIN2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human RIN2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RIN2

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Alternative Name: RIN2

Background:

Synonyms: MACS ,RAB5 interacting protein 2,Ras and Rab interactor 2,RAS association (RalGDS/AF-6) domain containing protein JC265,Ras association domain family 4,Ras inhibitor JC265,Ras interaction/interference protein 2,RASSF4,RIN 2,RIN2,RIN2

Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 120kDa

Calculated_MW: 100kDa/105kDa

Gene ID: 54453

UniProt: Q8WYP3